Comparison 9. Mesalamine versus sulfasalazine (alone or in combination with corticosteroids).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Induction of remission (CDAI < 150) or clinical improvement	2		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Salofalk (1.5 g/day)	1	30	Risk Ratio (M‐H, Random, 95% CI)	1.18 [0.82, 1.70]
1.2 Salofalk (3.0 g/day)	1	50	Risk Ratio (M‐H, Random, 95% CI)	0.94 [0.75, 1.18]
2 Adverse events	2		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 Salofalk (1.5 g/day)	1	30	Risk Ratio (M‐H, Random, 95% CI)	0.11 [0.01, 1.90]
2.2 Salofalk (3.0 g/day)	1	50	Risk Ratio (M‐H, Random, 95% CI)	0.54 [0.15, 1.93]