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. 2014 Nov 26;2014(11):CD007403. doi: 10.1002/14651858.CD007403.pub3

Ginsberg 1987.

Methods RCT, DB, parallel groups
Duration 14 days
Assessment on days 3, 14
Participants Acute mechanical low back pain
N = 40
Interventions Methylsalicylate (2.6%), ethylsalicylate (1.8%), glycol salicylate (0.9%), salicylic acid (0.9%), camphor (0.4%), menthol (5.5%), capsicum oleoresin (1.5%) ointment (Rado‐Salil), n = 20
Placebo ointment, n = 20
Frequency of application not stated
Outcomes PI: 100 mm VAS
Duration of confinement to bed
Muscular reflex contracture 5‐point scale
Spine mobility:
Schober's index
Finger‐floor distance
Lumbar extension
Patient global assessment: 5‐point scale
Use of rescue medication (paracetamol 250 mg tablets)
Amount of ointment used
Adverse events
Notes Oxford Quality Score: R1, DB2, W0. Total = 3/5
No analgesics, anti‐inflammatories, or physical treatments allowed other than rescue medication (max 45 x 250 mg paracetamol)
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method used to generate random sequence not described
Allocation concealment (selection bias) Unclear risk Method not described
Blinding (performance bias and detection bias) 
 All outcomes Low risk "Placebo was identical in appearance"
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants accounted for
Size High risk < 50 participants per treatment arm