Lester 1981.
Methods | RCT, DB, parallel groups Duration 7 days Assessment on days 3, 7 |
|
Participants | Sprained ankle Baseline pain slight to severe N = 42 (50 randomised: 4 ineligible, 4 lost to follow‐up) M = 20, F = 22 Age range 15 to 60+ years |
|
Interventions | Salicylic acid (2%), adrenal extract (1%), mucopolysaccharide polysulphate (0.2%) gel (Movelat), n = 20 Placebo gel, n = 22 |
|
Outcomes | Relief of pain Time to return to normal activity Adverse events Composite score based on above plus ankle range of movement, swelling Withdrawals |
|
Notes | Oxford Quality Score: R1, DB1, W0. Total = 2/5 Tubes of Movelat and placebo gel supplied by Luitpold‐Werk |
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method used to generate random sequence not described |
Allocation concealment (selection bias) | Unclear risk | Method not described |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Method not described |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | 4 participants lost to follow‐up (did not state group) |
Size | High risk | < 50 participants per treatment arm |