Moreira 2014.
Methods | Randomised controlled trial | |
Participants |
Participants: 40 preterm infants Mean birth weight: 1256 grams in control group and 1306 grams in NNS stimulation group Mean gestational age: 29.9 weeks in control group and 30.1 weeks in NNS stimulation group Setting: neonatal unit, Hospital de Clínicas da Universidade Federal do Paraná, Brazil Inclusion criteria: birth weight < 1500 grams, gestational age at birth ≤ 32 weeks, 5‐minute Apgar score ≥ 6, clinical (respiratory and haemodynamic) stability on enrolment and during the study, initiation of enteral feeding by oral or nasogastric tube associated or not with parenteral nutrition, and free and informed consent form signed by the parents. Exclusion criteria: grades III/IV intraventricular haemorrhage, clinical instability on enrolment or during the study, including necrotizing enterocolitis, sepsis, bronchopulmonary dysplasia and other clinical respiratory or haemodynamic instabilities, 5‐minute Apgar ≤ 5, presence of genetic syndromes, neurological disorders, as well as head, neck or central nervous system congenital malformations |
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Interventions |
Experimental group: infants received a 10‐minute NNS stimulation with a gloved finger before feeding, 3 times a day, 3 times a week, with the newborn on a supine, semiflexed position receiving perioral and oral stimulation Control: no NNS |
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Outcomes | Transition time to oral feeds | |
Notes | — | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "Newborns randomly and equally distributed into 2 groups" |
Allocation concealment (selection bias) | Unclear risk | Not reported |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Blinding of intervention ‐ unclear Blinding of outcome assessors ‐ unclear |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Complete follow‐up ‐ yes |
Selective reporting (reporting bias) | Unclear risk | Study protocol not obtained |