Table 1:
Baseline characteristics of individuals with hypertension in the CAC Consortium by CAC score categories.
| Variable | Overall (N=16,167) |
CAC=0 (N=5114) |
CAC 1–99 (N = 5202) |
CAC 100–399 (N=2928) |
CAC ≥400 (N=2923) |
P-value* |
|---|---|---|---|---|---|---|
| Age, years | 58.1 ± 10.6 | 52.9 ± 9.6 | 57.2 ± 9.7 | 61.7 ± 9.7 | 65.3 ± 9.6 | <0.001 |
| Women | 5795 (35.8%) | 2597 (50.8%) | 1789 (34.4%) |
846 (28.9%) | 563 (19.3%) | <0.001 |
| Men | 10372 (64.2%) | 2517 (49.2%) | 3413 (65.6%) |
2082 (71.1%) | 2360 (80.7%) | |
| Race | 0.07 | |||||
| White | 10557 (85.8%) | 3325 (85.9%) | 3361 (84.8%) | 1959 (85.9%) | 1912 (87%) | |
| Black | 519 (4.22%) |
169 (4.4%) |
187 (4.7%) |
95 (4.2%) |
68 (3.1%) |
|
| Hispanic | 490 (3.98%) |
161 (4.2%) |
159 (4.0%) |
76 (3.33%) | 94 (4.3%) |
|
| Hyperlipidemia | 10043 (62.1%) | 2821 (55.2%) | 3226 (62.0%) | 1959 (66.9%) | 2037 (69.7%) | <0.001 |
| Current Smoker | 1541 (9.5%) | 435 (8.5%) | 466 (9.0%) |
332 (11.3%) | 308 (10.5%) | <0.001 |
| Family History of CHD | 7711 (47.7%) | 2431 (47.5%) | 2504 (48.1%) | 1371 (46.8%) | 1405 (48.1%) | 0.68 |
| Diabetes | 2047 (12.7%) | 391 (7.7%) | 599 (11.5%) |
427 (14.6%) | 630 (21.6%) | <0.001 |
| 10-y ASCVD risk score | 12.1 ± 11.9 | 6.4 ± 6.8 | 10.7 ± 9.8 | 15.7±12.6 | 21.2 ± 14.8 | <0.001 |
| 10-y Framingham risk score | 15.9 ± 11.4 | 11.3 ± 7.6 | 15.2 ± 9.8 | 18.6 ± 12.2 | 22.7 ± 14.5 | <0.001 |
Continuous variables shown as mean±SD, categorical variables shown as n (%).
*
P-value was calculated for continuous variables using a nonparametric test for trend and for categorical variables using the Chi-square test.
ASCVD indicates atherosclerotic cardiovascular disease; CAC, coronary artery calcium; CHD, coronary heart disease.