Table 1:
Pregnancy outcomes.
Pregnancy outcome | CON (n=8) | SILD (n=10) | P-value |
---|---|---|---|
UPE (mg/day) at GD19 | 75.0 ± 43.8 | 63.5 ± 21.8 | 0.13 |
Birth weight combined sex (g) | 6.23 ± 0.05 | 6.83 ± 0.18 | 0.02 |
Birth weight females (g) | 6.16 ± 0.10 | 6.78 ± 0.17 | 0.02 |
Birth weight males (g) | 6.39 ± 0.07 | 6.96 ± 0.20 | 0.04 |
Total litter size | 9.3 ± 0.8 | 10.9 ± 1.0 | 0.23 |
Viable litter size (PD 3) | 7.9 ± 1.0 | 9.6 ± 0.9 | 0.23 |
Mean ± s.e.m. CON, control; GD, gestational day; PD, postnatal day; SILD, sildenafil; UPE, urine protein excretion. Three CON and one SILD litters were excluded due to lost to follow up of the offspring.