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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Hypertension. 2019 May;73(5):1120–1127. doi: 10.1161/HYPERTENSIONAHA.118.12454

Table 2:

MAP progression per week from week five until week twenty.

Sex Parameter Group Intercept Pintercept r Pr
All MAP CON 97.1 (90.2; 104.0) 0.60 2.4 (2.0; 2.8) 0.03
SILD 98.2 (95.6; 100.8) 2.1 (2.0; 2.3)
MAPday-time CON 92.1 (85.5; 98.8) 0.13 2.6 (2.2; 3.0) 0.001
SILD 95.4 (92.9; 97.9) 2.2 (2.0; 2.3)
MAPnight-time CON 102.8 (94.7; 111.0) 0.43 2.2 (1.7; 2.7) 0.88
SILD 100.8 (97.7; 103.9) 2.2 (2.0; 2.3)
Male MAP CON 95.3 (84.8; 105.8) 0.68 2.6 (2.0; 3.2) 0.02
SILD 96.7 (92.8; 100.6) 2.1 (1.9; 2.3)
MAPday-time CON 90.4 (80.6; 100.3) 0.25 2.8 (2.1; 3.5) 0.002
SILD 94.1 (90.5; 97.7) 2.1 (1.9; 2.3)
MAPnight-time CON 102.1 (89.3; 114.9) 0.45 2.3 (1.5; 3.1) 0.67
SILD 99.0 (94.3; 103.7) 2.2 (1.9; 2.5)
Female MAP CON 98.0 (89.3; 106.8) 0.46 2.3 (1.8; 2.7) 0.34
SILD 100.0 (96.6; 100.4) 2.2 (2.0; 2.3)
MAPday-time CON 93.1 (84.3; 102.0) 0.17 2.5 (2.0; 3.0) 0.11
SILD 96.8 (93.4; 100.2) 2.2 (2.0; 2.4)
MAPnight-time CON 102.9 (93.0; 113.1) 0.98 2.1 (1.9; 2.4) 0.89
SILD 103.0 (99.1; 106.9) 2.1 (1.6; 2.0)

Mean arterial pressure (MAP) progression in prenatal sildenafil treated (SILD; n=22) and control (CON; n=15) offspring for combined sexes and separated for male (SILD: n=12 vs CON: n=8) and female (SILD: n=10 vs CON: n=7) offspring as analyzed with linear mixed model. Mean (95% confidence interval). The intercept is at five weeks of age. r = slope per week, from week five until twenty.