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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Mol Microbiol. 2019 Feb 17;111(4):1039–1056. doi: 10.1111/mmi.14207

Figure 8: Proposed model for the function of YpdA in the context of bacillithiol cycling.

Figure 8:

Bacillithiol is oxidized to bacillithiol disulfide through reaction with oxidants or through consumption by enzymes (e.g. Brx enzymes reducing S-bacillithiolated proteins to yield BSSB). YpdA recycles BSSB to maintain the reduced BSH pool.