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. Author manuscript; available in PMC: 2019 Dec 13.
Published in final edited form as: J Phys Chem B. 2018 Oct 10;122(49):11702–11720. doi: 10.1021/acs.jpcb.8b07768

Table 2.

Folding kinetics parameters.a

8-state 2-state
[GdmCl] 2 M 2.25 M 2.5 M 2 M 2.25 M 2.5 M
ε1F 0.16 0.16 0.16 0.16 0.16 0.16
ε1U 0.26 0.28 0.28 0.26 0.28 0.28
ε2F 0.71 0.69 0.70 0.71 0.69 0.69
ε2U 0.55 0.49 0.48 0.54 0.49 0.47
ε12F 0.84 0.83 0.82 0.84 0.83 0.82
ε12F 0.65 0.64 0.64 0.65 0.64 0.63
εFDA1 0.90 0.90 0.89 0.90 0.90 0.89
εUDA1 0.79 0.78 0.77 0.78 0.78 0.77
εFDA2 0.30 0.30 0.32 0.30 0.30 0.32
εUDA2 0.22 0.21 0.20 0.21 0.21 0.20
k 1.24 (±0.06) 0.91 (±0.03) 0.85 (±0.04) 1.32 (±0.06) 0.97 (±0.03) 0.92 (±0.05)
pF 0.65 (±0.01) 0.50 (±0.01) 0.29 (±0.01) 0.65 (±0.01) 0.51 (±0.01) 0.30 (±0.01)
kb1 5.97 (±1.05) 4.71 (±0.45) 5.35 (±0.71)
pb1b 0.99 0.99 0.99
kb2 1.99 (±0.90) 1.59 (±0.39) 1.36 (±0.38)
pb2b 0.99 0.99 0.98
a

Errors are standard deviations calculated from the curvature at the maximum of the likelihood function.

b

pb1 and pb2 correspond to the values at the reference photon count rate of 100 ms−1.