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. 2019 Apr 10;9:5847. doi: 10.1038/s41598-019-42396-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Reduced cell lysis of C. trachomatis infected primary human Sertoli compared with McCoy cells. Phase contrast micrographs (A) and one-step infectivity growth profiles and chromosome replication (B) of C. trachomatis in Sertoli and McCoy cells at 24 hourly intervals up to 96 hours post infection. Values are expressed as means ± SD of four replicates from two independent experiments. Representative images of ten chlamydial inclusions per condition are shown. White arrows indicate inclusions. *cell monolayer vs culture medium p < 0.01; ^#cell monolayer vs culture medium p < 0.05.