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. 2019 Apr 10;5:13. doi: 10.1038/s41523-019-0108-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Survival of xenograft-bearing mice following HYPERTAM. NSG mice endpoints (tumor volume ≥ 1000 mm³) shown as Kaplan–Meier plots for the different treatment groups of the MCF7 (a, c) and MDA-MB-231 (b, d) tumor models. CTRL (untreated), HD (HYP dark), TAM (tamoxifen only), HTD (HYP+TAM dark), HL (HYP-PDT), HTL (HYPERTAM). The error bars represent STD from the mean of seven parallels. The statistical significance was calculated using the log-rank (Mantel–Cox) test; ns p ≥ 0.05, *p < 0.05 and **p < 0.005