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. 2019 Apr 4;9:204. doi: 10.3389/fonc.2019.00204

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Copyright © 2019 Colafati, Voicu, Carducci, Caulo, Vinci, Diomedi-Camassei, Merli, Carai, Miele, Cacchione, Tomà, Locatelli and Mastronuzzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Survival analysis with Kaplan-Meier curves for the type of treatment administered to the patients in our cohort. Patients treated with radiotherapy, Nimotuzumab and Vinorelbine (label = “1,” green line, median TTP: 7 months, 95% CI 5.9–8.1 months) presented significantly higher time to progression (TTP) than patients treated with radiotherapy and Themozolomide (label = “0,” violet line, median TTP: 4 months, 95% CI 2.6–5.3 months, log rank test: p < 0.027). The other parameters (not shown) were not associated with significant differences in TTP (p = NS).