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. 2019 Apr 4;10:689. doi: 10.3389/fmicb.2019.00689

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Copyright © 2019 Otero, García-Rodríguez, Cano-Sarabia, Maspoch, Marcos, Cortés and Llagostera.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Confocal images of the x, y, and z scans of the in vitro Caco-2/HT29/Raji-B lymphocytes co-culture model. The results obtained with the non-treated (A), bacteriophage-treated (B) and PPE (C) treated cultures at 2 h are shown. Cell nuclei were stained with Hoechst 33242 (blue), bacteriophages with SYBR gold (green), and liposomes with Vybrant Dil (red). The plasma membrane was stained with CellMask DeepRed (gray). Red squares indicate the regions where the stained phages (B) or PPE (C) were visualized. Scale bars, 20 μm.