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Metabolic Conditions Associated With New Agents and Suggested Management
| Therapeutic Target | Liver Enzyme Abnormality | Lipids/Creatine Kinase |
|---|---|---|
| TNF | Continue: if <2x ULN Stop: >2x ULN or (+) Hepatitis B or autoimmune hepatitis |
Continue |
| Integrin | Continue, but monitor | Continue |
| IL 12/23 | Continue | Continue |
| JAK | Continue | Continue, but monitor |
IL: interleukin; JAK: Janus kinase; ULN: upper limit of normal
