Table 1.

Summary of the biochemical and molecular findings among the family members

Family member	Clinical FH diagnosis	TC mmol/lL	TG mmol/L	HDL-C mmol/L	LDL-C mmol/L	dbSNP ID	Predicted effect
Proband	Definite FH	10.0	1	1.5	8.6	LDLR: rs121908026	Probably Damaging
Older brother (Hypercholesterolemic)	Probable FH	9.6	0.6	0.3	7	LDLR: rs121908026	Probably Damaging
Grandfather	Definite FH	9.3	1.4	1	7.7	LDLR: rs121908026	Probably Damaging
Twin, youngest brother	Definite FH	10.6	0.7	1.8	8.6	LDLR: rs121908026	Probably Damaging
						ABCG8: rs11887534	Possibly Damaging
Twin, youngest brother	Definite FH	10.8	0.6	1.7	8.8	LDLR: rs121908026	Probably Damaging
						ABCG8: rs11887534	Possibly Damaging
Eldest brother (Normolipaemic)	Possible FH	5.2	0.4	2.6	2.4	LDLR: rs2738442	Benign
						ABCG8: rs11887534	Possibly Damaging
Mother	Possible FH	5.3	0..9	2	2.8	LDLR: rs2738442	Benign
						ABCG8: rs11887534	Possibly Damaging