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. 2019 Apr 9;15:1744806919836569. doi: 10.1177/1744806919836569

Figure 4.

Figure 4.

The proportion and electrophysiological characteristics of Cav3 currents in SG neurons of PSNL rats. (a) The proportion of neurons with or without IT in sham (41/69, 59.4%) and PSNL rats (46/60, 76.7%). (b) Peak amplitudes of IT (Vhold = −110 mV) from sham (n = 41) and PSNL (n = 46) rats. (c) Current density (peak current amplitude divided by cell’s capacitance) against test potential of IT from sham (n = 41) and PSNL (n = 46) rats. (d) and (e) Representative activation and inactivation traces of IT in SG neurons from sham and PSNL rats. Activation currents (d) were evoked by the voltage steps from −110 mV (Vhold) to test potentials from −70 mV through −40 mV in a 5-mV step. Inactivation currents (e) were evoked by test steps to −50 mV after a 0.5-s prepulse at potentials from −60 mV to −110 mV in a 5-mV step. (f) Steady-state activation and inactivation of IT in the sham and PSNL rats. (g) Bar graphs of half-activation or half-inactivation potentials of IT (activation: sham, n = 11, PSNL, n = 16; inactivation: sham, n = 14, PSNL, n = 22). *p < 0.05, compared with sham control. PSNL: partial sciatic nerve ligation.