. 2019 Apr 11;20:177. doi: 10.1186/s12859-019-2775-8

Table 2.

The top-ranked genes across the risk levels of death by the MFSelector method

AC				SCC
Ascending		Descending		Ascending	Descending
GNL3L^**	FKBP3 ^**	RGS2 ^**	ARF6^a	MMP1	ATIC
RALY^**	FRAT1 ^**	POLK^**	C21orf91^a	S100A2	SART3
TBC1D10A^**	GRK7^**	SHOC2 ^**	ELK3 ^a	TP53AIP1	CRLS1
CDK19 ^**	HINFP ^**	ADD3 ^**	EPS15^a	DEFB1	DST
CRY2 ^**	INPP5K ^**	EXOC1 ^**	IBTK^a	EIF2S1	EMG1
EPHB2 ^**	KLF13 ^**	KRAS ^**	KPNA5^a	HSPG2	FES
MARK4 ^**	MC4R ^**	SLC4A1AP^**	MTF2 ^a	IBTK	HSP90AB1
NAT6 ^**	MDH2 ^**	DMTF1^**	MYL12A^a	PAK2	PEBP1
PLEKHJ1 ^**	MKNK2 ^**	FRYL^**	PPP1CB^a	SH2D3C	PMS1
RAB1B ^**	NARF ^**	ITGAV^**	RUFY2^a	SPHK1	PPP6C
RHOT2 ^**	PACSIN2 ^**	KIF5B^**	RWDD1^a	UBR7
TMEM222 ^**	PRKACA ^**	SOD2^**	STX7^a
ANP32A ^**	RARA ^**	USO1^**	TBK1^a
CORO1B ^**	RFXANK ^**
FNTB ^**	SIRT2 ^**
MAP 7D1 ^**	STAT3 ^**
PI4KA ^**	TACR2 ^**
SHBG ^**	TMEM39B^**
THRA ^**	TPPP ^**
TINF2 ^**	TSSC4 ^**
UPF1 ^**	TUFM ^**
ZNF142 ^**	URGCP ^**
DLG5 ^**	WASF2 ^**
EP400 ^**	YIF1A ^**

Note: * the corresponding q-value of DE_total < 0.1; ** q-value< 0.05; ^a q-value = 0.05; AC: lung adenocarcinoma; SCC: lung squamous cell carcinoma; Ascending: a monotonically expressed gene in the ascending order; descending: a monotonically expressed gene in the descending order. If the cutoff of q-value was set at 0.1, there were 166 ascending MEGs and 172 descending MEGs for the AC subtype. However, no MEGs exist for the SCC subtype at the level of 0.1