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. 2019 Apr 11;16:82. doi: 10.1186/s12974-019-1458-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Neuropathic pain is reduced by GPR34 antagonism. The PWT in the ipsilateral (Ipsi) (a) and contralateral (Contra) (b) side of WT mice with L4 nerve injury. Mice were intrathecally administered the GPR34 antagonist once a day for 14 days after nerve injury (n = 8), and the von Frey test was performed on days 3, 7, and 14. Values are mean ± SEM. *p < 0.05 (one-way RM ANOVA with Bonferroni adjustment or the nonparametric RM ANOVA on ranks with Dunnett’s adjustment)