Table 4.
Amino acid substitutions identified in HAs of pH1N1 viruses sequenced during 2009–2017. Amino acid substitutions of pH1N1 are reported in comparison to A/California/07/2009. Bordered cells indicate substitutions in receptor binding site. Deleterious mutations were predicted by online server PROVEAN and are indicated in bold
*Substitution Q240R was found in 16 viruses isolated exclusively from Iran