Table 3.

Cost of the prophylaxis of chemotherapeutic agents for 6 months duration

Type of prophylaxis agent	Recommended dosage for 6 months	Cost per pack	Total cost
Nitrofurantoin tablet 50mg	Once daily for 6 months	£1.84/pack (28 tablets)	£5.52
Estriol pessary 500 mg	Once daily for 2 weeks, then once a fortnight subsequently (25 pessaries)	£4.92/pack (15 pessaries)	£8.20
Cranberry extract capsule 500 mg	Once daily for 6 months	£11.96/pack (100 capsules)	£21.53
Fosfomycin sachet 3mg	Once monthly for 6 months	£4.86/sachet	£29.16
D-mannose powder 2gm	Once daily for 6 months	£34.99/pack (200gm)	£63.00
Trimethoprim-sulfamethoxazole tablet 480 mg	Once daily for 6 months	£13.83/pack (28 tablets)	£82.98

Proportionately D-mannose and Trimethoprin-sulfmethaxazole rank high (63.00 vs, 83.00). Nitrofurantoin is relatively a cheap drug and based on tolerability and efficacy. Prices are based on British Formulary (2015) and are at best an estimate