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. 2019 Apr 10;19:59. doi: 10.1186/s12883-019-1274-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Histopathological and immunohistochemical characteristics of the cerebral amyloidoma. Large concentric sheets of Congo Red stained amyloid around an arteriole displaying the characteristic apple-green birefringence under polarized light and leading to an extraordinary thickening of the vessel wall (a), (original magnification × 25). Demonstration of the marked perivascular inflammatory reaction by visualizing macrophages (b) (CD68 immunostaining, original magnification × 200), T-lymphocytes (c), (CD3 immunostaining, original magnification × 100) and B-lymphocytes (d), (CD20 immunostaining, original magnification × 100). Hemosiderin-loaden macrophages indicating previous intraparenchymal microhemorrhage were encountered only very sporadically (arrows in e), (Prussian blue staining, original magnification × 50)