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Effect of AC on HbA1c and kidney/weight ratio in each group (±SE).
| Group | HbA1c (%) | K/W |
|---|---|---|
| NC | 4.12±0.11 | 5.88±0.15 |
| DN | 7.61±0.31∗ | 7.47±0.70∗ |
| DN+M | 7.20±0.42∗ | 5.14±0.41# |
| DN+AC | 6.53±0.41∗# | 5.20±0.43# |
Note: NC: normal control mice, DN: diabetic nephropathy mice, DN+M: DN mice given 180 mg/kg metformin, and DN+AC: DN mice given 300 mg/kg AC. K/W: Kidney/weight ratio. ∗: P<0.05 compared with the NC group; #: P<0.05 compared with the DN group.
