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Effect of tolfenamic acid on motor deficits in R6/1 mice. R6/1 mice exhibited progressive weakening in muscle strength in the grip strength test (a) and a decrease in fall latency time (b) in the rotarod test compared with control mice. Tolfenamic acid treatment improved performance in the rotarod test, but not in the grip strength test. All results are expressed as mean ± SD. n = 7–8; # p < 0.05 and ## p < 0.01 versus control; ∗ p < 0.05 and ∗∗ p < 0.01 versus model.
