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Therapeutic efficacy of EpCAM-specific CAR-NK-92 cells combined with regorafenib for human colorectal cancer xenografts established with HCT-8 cells. (a) Schematic diagram showing the treatment program of the mice. (b) The tumor growth curves during the experiment. (c) Luminescence images showing the tumor size at the end of the treatment. (d) Tumor weight at the end of treatment. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.
