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. 2019 Mar 26;2019:2745352. doi: 10.1155/2019/2745352

Table 6.

Immunohistochemical staining intensity (pixels) for p53, Bax, caspase-3, and Bcl-2 in liver normal control, APAP, APAP + peel extract, APAP + naringin, and APAP + naringenin groups.

Parameter p53 × 103 Bax × 103 Caspase − 3 × 103 Bcl − 2 × 103
Group
Normal control 2.125 ± 0.686 0.379 ± 0.119 0631 ± 0.046 10.18 ± 0.585
APAP 69.277 ± 3.075a 91.585 ± 14.270a 15.426 ± 2.467a 0.580 ± 0.087a
APAP + peel extract 1.007 ± 0257b 0.497 ± 0.096b 0.697 ± 0.157b 125.57 ± 11.012b
APAP + naringin 0.828 ± 0123b 0.387 ± 0.116b 0.482 ± 0.054b 197.505 ± 33.008b
APAP + naringenin 1.653 ± 0424b 0.207 ± 0.126b 1.740 ± 0.366b 190.504 ± 9.905b

Data are expressed as mean ± SE. aSignificantly different from normal value at p < 0.05. bSignificantly different from the APAP value at p < 0.05.