Table 2. Models for the Risk of Alopecia Areata Associated With Major Depressive Disorder.
| Model | HR (95% CI) | P Value |
|---|---|---|
| Unadjusted model | ||
| Major depressive disorder | 1.76 (1.62-1.91) | <.001 |
| Multivariable adjusted modela | ||
| Major depressive disorder | 1.90 (1.67-2.15) | <.001 |
| Age | 0.43 (0.40-0.46) | <.001 |
| Male sex | 0.81 (0.75-0.86) | <.001 |
| Socioeconomic statusb | ||
| 2 | 0.99 (0.90-1.10) | .87 |
| 3 | 1.15 (1.04-1.27) | .01 |
| 4 | 1.22 (1.11-1.35) | <.001 |
| 5 | 1.43 (1.29-1.59) | <.001 |
| Charlson Comorbidity Index | 1.16 (1.07-1.26) | <.001 |
| Alcohol use | 0.93 (0.87-1.00) | .06 |
| Smoking | ||
| Current | 1.43 (1.33-1.54) | <.001 |
| Ex-smoker | 1.13 (1.01-1.27) | .03 |
| Antidepressant use | 0.57 (0.53-0.62) | <.001 |
Abbreviation: HR, hazard ratio.
a
Observations with missing data were omitted from the models.
b
Higher number indicates more severe socioeconomic deprivation using the Townsend Deprivation Index.