Figure 4.
Stimulation of cytokine production by heat-killed and b-eliminated cells from Candida albicans, Candida tropicalis, Candida guilliermondii, Candida krusei, and Candida auris.
Notes: Yeast cells were heat-killed (HK), b-eliminated, or subjected to both treatments before being coincubated with human PBMCs for 24 hours. The supernatants of interactions were collected and used to quantify the cytokine levels. * P<0.05, when compared with the cytokine level stimulated by C. albicans cells under the same treatment. Abbreviations: PBMCs, peripheral blood mononuclear cells; TNFα, tumor necrosis factor alpha; C. alb, Candida albicans; C. tro, Candida tropicalis; C. gui, Candida guilliermondii; C. kru, Candida krusei; C. aur, Candida auris.