Table 3.
Evaluation of primary NAT-SLNs prepared for the selection of appropriate SAA
| Solid lipid | SAA | Average PS (r.nm) | Zeta potential | PDI | Visual examination | |
|---|---|---|---|---|---|---|
| After preparation | Overnight storage | |||||
| Precirol ATO 5 | Kolliphor EL | 163 | 30.3 | 0.347 | SP | P |
| Pluronic f68 | 42 | 26.7 | 0.224 | NP | NP | |
| Tween 80 | 65 | 24.7 | 0.248 | NP | SP | |
| Solutol HS 15 | 197 | 23.8 | 0.373 | P | P | |
| Gelucire 50/13 | 72 | 28.9 | 0.375 | SP | SP | |
| Transcutol P | 86 | 34.8 | 0.285 | SP | P | |
Abbreviations: P, precipitation; SP, slight precipitation; NP, no precipitation; r.nm, radius in nanometers; PDI, polydispersity index; PS, particle size.