MEDLINE (Ovid SP)

1 Hypoglycemia/ 2 (Hypoglycemi* or hypoglycaemi*).tw,kf. 3 Healthy Volunteers/ 4 (healthy participant or healthy participants or healthy subject or healthy subjects or healthy volunteer or healthy volunteers or human volunteer or human volunteers or normal volunteer or normal volunteers).tw,kf. 5 healthy people.tw,kf. 6 healthy persons.tw,kf. 7 1 or 2 or 3 or 4 or 5 or 6 8 Glucose/ 9 (glucose or sugar).tw,kf. 10 8 or 9 11 drug administration routes/ or administration, inhalation/ or exp administration, oral/ or Administration, Rectal/ 12 administ*.tw,kf. 13 11 or 12 14 (buccal* or sublingual* or oral* or by mouth or rectal* or tablet* or liquid* or gel or gels or sachet* or spray or sprays or tongue or cheek or swallow* or administration route*).tw,kf. 15 Solutions/ 16 Tablets/ 17 Cheek/ 18 Gels/ 19 14 or 15 or 16 or 17 or 18 20 7 and 10 and 13 and 19 21 limit 20 to (case reports or comment or congresses or editorial or letter) 22 20 not 21 23 22 not (animals/ not humans/) 24 remove duplicates from 23

Cochrane Central Register of Controlled Trials (Cochrane Register of Studies Online)

1 Hypoglycemia/ 2 (Hypoglycemi* or hypoglycaemi*).tw,kf. 3 Healthy Volunteers/ 4 (healthy participant or healthy participants or healthy subject or healthy subjects or healthy volunteer or healthy volunteers or human volunteer or human volunteers or normal volunteer or normal volunteers).tw,kf. 5 healthy people.tw,kf. 6 healthy persons.tw,kf. 7 1 or 2 or 3 or 4 or 5 or 6 8 Glucose/ 9 (glucose or sugar).tw,kf. 10 8 or 9 11 drug administration routes/ or administration, inhalation/ or exp administration, oral/ or Administration, Rectal/ 12 administ*.tw,kf. 13 11 or 12 14 (buccal* or sublingual* or oral* or by mouth or rectal* or tablet* or liquid* or gel or gels or sachet* or spray or sprays or tongue or cheek or swallow* or administration route*).tw,kf. 15 Solutions/ 16 Tablets/ 17 Cheek/ 18 Gels/ 19 14 or 15 or 16 or 17 or 18 20 7 and 10 and 13 and 19 21 remove duplicates from 20

Embase (Ovid SP)

1 hypoglycemia/ or insulin hypoglycemia/ or nocturnal hypoglycemia/ 2 experimental hypoglycemia/ 3 normal human/ 4 (healthy participant or healthy participants or healthy subject or healthy subjects or healthy volunteer or healthy volunteers or human volunteer or human volunteers or normal volunteer or normal volunteers or healthy people or healthy persons).tw. 5 1 or 2 or 3 or 4 6 glucose/ 7 (glucose or sugar).tw. 8 6 or 7 9 drug administration route/ 10 oral drug administration/ 11 enteral drug administration/ 12 sublingual drug administration/ 13 exp buccal drug administration/ 14 rectal drug administration/ 15 administ*.tw. 16 9 or 10 or 11 or 12 or 13 or 14 or 15 17 (buccal* or sublingual* or oral* or by mouth or rectal* or tablet* or liquid* or gel or gels or sachet* or spray or sprays or tongue or cheek or swallow* or administration route*).tw. 18 cheek/ 19 aerosol/ or drug solution/ or gel/ or lozenge/ or oral drops/ or oral spray/ or paste/ or exp tablet/ 20 17 or 18 or 19 21 5 and 8 and 16 and 20 22 limit 21 to (books or "book review" or chapter or conference abstract or conference paper or "conference review" or editorial or letter or note) 23 21 not 22 24 23 not ((exp animal/ or nonhuman/) not exp human/) 25 remove duplicates from 24 26 limit 25 to embase

CINAHL Plus with full text (EBSCOhost Research Databases)

S1 (MH "Hypoglycemia") S2 TI ( (Hypoglycemi* or hypoglycaemi*) ) OR AB ( (Hypoglycemi* or hypoglycaemi*) ) S3 TI ( (healthy participant or healthy participants or healthy subject or healthy subjects or healthy volunteer or healthy volunteers or human volunteer or human volunteers or normal volunteer or normal volunteers or healthy people or healthy persons) ) OR AB ( (healthy participant or healthy participants or healthy subject or healthy subjects or healthy volunteer or healthy volunteers or human volunteer or human volunteers or normal volunteer or normal volunteers or healthy people or healthy persons) ) S4 S1 OR S2 OR S3 S5 (MH "Glucose") S6 TI ( glucose or sugar ) OR AB ( glucose or sugar ) S7 S5 OR S6 S8 (MH "Drug Administration Routes") OR (MH "Administration, Oral+") OR (MH "Administration, Rectal") OR (MH "Administration, Inhalation") S9 TI administ* OR AB administ* S10 S8 OR S9 S11 TI ( (buccal* or sublingual* or oral* or by mouth or rectal* or tablet* or liquid* or gel or gels or sachet* or spray or sprays or tongue or cheek or swallow* or administration route*) ) AND AB ( (buccal* or sublingual* or oral* or by mouth or rectal* or tablet* or liquid* or gel or gels or sachet* or spray or sprays or tongue or cheek or swallow* or administration route*) ) S12 (MH "Solutions") OR (MH "Tablets") OR (MH "Aerosols") OR (MH "Gels") S13 (MH "Cheek") S14 (MH "Tongue") S15 S11 OR S12 OR S13 OR S14 S16 S4 AND S7 AND S10 AND S15

ClinicalTrials.gov (standard search)

Condition or disease: Hypoglycemia Other terms: Hypoglycaemia Study type: Interventional Studies Intervention/treatment: Glucose

World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) Search Portal (standard search)

hypoglycemia OR hypoglycaemia

EU Clinical Trials Register

(hypoglycemia OR hypoglycaemia) AND glucose