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. 2019 Apr 11;2019(4):CD013283. doi: 10.1002/14651858.CD013283.pub2
Study ID Resolution of symptoms Time to resolution of symptoms Blood or plasma glucose concentration at 20 minutes Resolution of hypoglycaemia Time to resolution of hypoglycaemia Adverse events Treatment delay Severe/serious
 adverse events
 (specify)
Chlup 2009 NI NI Plasma glucose tested in finger‐prick capillary blood NI NI NI NI NI
Barennes 2005 NI NI Blood glucose concentrations, collected through finger prick Treatment failure rate, proportion of children not reaching a blood glucose concentration of ≥ 90 mg/dL during the study period. These data were used to determine 'resolution of hypoglycaemia within 80 minutes'.
Early treatment failure rate: proportion of children with no blood glucose gain at 20 minutes. These data were used to determine 'resolution of hypoglycaemia within 20 minutes'
Time to glucose concentration normalisation Any adverse event NI NI
Slama 1990 Clinical recovery (complete symptomatic relief) Clinical recovery time Plasma glucose determination, using a glucose oxidase method NI NI NI NI NI
Gunning 1978 NI NI Number of participants with increased blood glucose at 20 minutes NI NI NI NI NI
aIn addition to definition of endpoint measurement, description who measured the outcome (AO: adjudicated outcome measurement; IO: investigator‐assessed outcome measurement; SO: self‐reported outcome measurement).
ND: not defined; NR: not reported; NI: not investigated.