| Study ID | Intervention(s) and comparator(s) | Participants included in analysis (N) | Deaths (N) | Deaths (% of participants) | Participants with at least one adverse event (N) | Participants with at least one adverse event (%) | Participants with at least one severe/serious adverse event (N) | Participants with at least one severe/serious adverse event (%) |
| Chlup 2009 | I: buccal treatment | — | — | — | — | — | — | — |
| C: oral treatment | — | — | — | — | — | — | — | |
| Barennes 2005 | I: sublingual treatment | 27 | 0 | 0 | 0 | 0 | 0 | 0 |
| C: oral treatment | 15 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Slama 1990 | I: combined oral + buccal treatment | — | — | — | — | — | — | — |
| C: oral treatment | — | — | — | — | — | — | — | |
| Gunning 1978 | I: buccal treatment | — | — | — | — | — | — | — |
| C: oral treatment | — | — | — | — | — | — | — | |
| —: denotes not reported C: comparator; I: intervention; N: number of participants. | ||||||||
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