Table 4. Number of Injections and Negative Binomial Regression Analysis From Baseline to Month 12 for the Full Analysis Seta,b.
| Characteristic | Treatment Effectc | |
|---|---|---|
| Ranibizumab (n=141) | Aflibercept (n=137) | |
| No. of injections | ||
| Mean (SD) | 9.7 (2.77) | 9.7 (2.55) |
| Median (range) | 10.0 (1-13) | 10.0 (3-13) |
| LSM,d (95% CI) | 11.20 (10.88-11.53) | 11.16 (10.83-11.50) |
Abbreviation: LSM, least squares means.
a
Model: Number of Injections = Treatment + log (Follow-up Period in Years) (offset).
b
Follow-up period: from baseline (first dosing) to visit month 12 (exclusive).
c
Treatment effect: rate ratio of ranibizumab vs aflibercept; treatment effect, 1.00 (95% CI, 0.96-1.05; P = .86).
d
Unit for least squares means: number of injections per year.