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Intestinal and plasma PK of RDX8940 and glucagon-like peptide-1 (GLP-1) induction in mice at 1, 4, and 8 h after a single oral dose of RDX8940 30 mg/kg. Data are expressed as means ± SE (n = 6 for each dosing set at each time point). BQL, below quantification level; Dist, distal; GI, gastrointestinal; GLP-1, glucagon-like peptide-1; LLOQ, lower limit of quantification; PK, pharmacokinetics; Prox, proximal.
