Table 2. Clinicopathologic characteristics of DLBCL patients.
Characteristic | All patients | TIM3 low | TIM3 high | P | |
---|---|---|---|---|---|
Gender (n) | Male | 32 | 24 | 8 | 0.20* |
Female | 38 | 23 | 15 | ||
Median Age (yrs) | 69 | 70 | 68 | 0.47# | |
Performance Status (n) | 0–1 | 35 | 24 | 11 | 0.08* |
2+ | 17 | 11 | 6 | ||
NA | 18 | ||||
Stage (n) | 1-2 | 28 | 21 | 7 | 0.22* |
3-4 | 38 | 23 | 15 | ||
NA | 4 | ||||
IPI Score (n) | 0-2 | 33 | 26 | 7 | 0.02* |
3+ | 24 | 12 | 12 | ||
NA | 13 | ||||
Treatment (n) | R-CHOP | 45 | 31 | 14 | 0.68* |
Other | 25 | 16 | 9 |
*Chi-square test.
#t-test.
Abbreviations: TIM-3, T cell immunoglobulin and mucin domain-containing protein-3; n, number; yrs, years; GCB, germinal center; NA, not available; IPI, International Prognostic Index; R-CHOP, rituximab, cyclophosphamide, doxorubicin, oncovin, prednisone.