Table 1.

Factors found to impact adherence

Disease factors	Therapy factors	Healthcare factors	Patient factors	Social factors
Disease treated5	Side-effects8,12,13	Relationship/communication with physician6,14,15	Gender9,16,17	Socioeconomic status6,10,17,19–21
Primary versus secondary disease prevention11,17,20,22	Dosing regimen/frequency5,8,22–24	Self-monitoring25	Age5,17	Level of education/health literacy9,26
Comorbidity10	Drug class10,12,13,27,28	Cost/co-payments6,8,20,22,29–31	Making time for appointments6,29	Ethnicity16
Depression10,14,32	Combination pill33–37	Routine place of care6,30	Stress/anxiety14	Minority status10
Diabetes10,17		Routine physician6,15,30	Forgetfulness6,14	Social support18
Duration of treatment20		Practitioner disagreement with guidelines14	Lack of understanding8,14,15,29
		Coronary artery calcium (CAC) screening39	Alcohol consumption39
			Patient beliefs/perception of drugs6,8,14,15,21