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. 2019 Feb 1;51(3):90–96. doi: 10.1152/physiolgenomics.00001.2019

Fig. 3.

Fig. 3.

Renal afferent nerve activation is involved in calcitonin gene-related peptide (CGRP) release and increased cortical renal perfusion. A: plasma CGRP levels was measured by ELISA from C57BL/6J mice infused with either vehicle or SMM-295 (6 mg/kg). n = 6 mice per group. *P = 0.0068 significant difference between groups. B: measurement of renal cortical perfusion by laser Doppler flowmetry during control and SMM-295 (6 mg/kg) administration in mice treated with capsaicin to ablate renal afferent nerve activity. n = 6 mice per group. *P < 0.0001 significant difference between groups.