Table 2.
Values of systolic blood pressure (SBP in mmHg) measured by tail plethysmography in Wistar rats and spontaneously hypertensive rats (SHRs) before and after treatment for 30 days with HgCl2.
| Wistar CT n = 5 |
Wistar Hg n = 5 |
SHR CT n = 5 |
SHR Hg n = 5 |
|
|---|---|---|---|---|
| SBP – Day 0 (mmHg) | 123 ± 13 | 131 ± 15 | 205 ± 15 | 198 ± 22 |
| SBP – Day 7 (mmHg) | 119 ± 4 | 132 ± 9 | 221 ± 18 | 197 ± 18 |
| SBP – Day 14 (mmHg) | 115 ± 10 | 135 ± 9 | 219 ± 9 | 199 ± 29 |
| SBP – Day 21 (mmHg) | 132 ± 17 | 142 ± 14 | 200 ± 13 | 199 ± 9 |
| SBP – Day 30 (mmHg) | 117 ± 6 | 143 ± 11 | 220 ± 21 | 232 ± 19# |
Results represent the mean ± SD; n: number of animals used. One-way ANOVA, post hoc Tukey's for all groups.
#
p < 0.05 vs. SHR treated with mercury at day 0