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. 2019 Apr 11;14(4):e0215065. doi: 10.1371/journal.pone.0215065

Table 4. Gene ontology (GO) based on known genes harboring high or moderate impact SNPs.

GO biological process complete Fold Enrichment P-value
Immune responses
Phagosome-lysosome fusion involved in apoptotic cell clearance (GO:0090389) 82.97 1.20E-02
Phagolysosome assembly involved in apoptotic cell clearance (GO:0090387) 82.97 1.20E-02
Isotype switching to IgA isotypes (GO:0048290) 82.97 1.20E-02
Negative regulation of T-helper 1 type immune response (GO:0002826) 82.97 1.20E-02
Interleukin-33-mediated signaling pathway (GO:0038172) 41.48 2.38E-02
Heat tolerance
Homoisothermy (GO:0042309) 82.97 1.20E-02
Neurohypophysis development (GO:0021985) 82.97 1.20E-02
Response to UV-B (GO:0010224) 11.85 1.27E-02
Cerebrospinal fluid secretion (GO:0033326) 41.48 2.38E-02
Signaling pathways
Detection of light stimulus involved in sensory perception (GO:0050962) 9.76 1.83E-02
Detection of light stimulus involved in visual perception (GO:0050908) 9.76 1.83E-02
Regulation of non-canonical Wnt signaling pathway (GO:2000050) 9.22 2.03E-02
Negative regulation of Rac protein signal transduction (GO:0035021) 20.74 4.71E-02
Cellular development
Exon extension (GO:0048675) 7.32 8.39E-03
Peripheral nervous system axon ensheathment (GO:0032292) 7.93 2.70E-02