. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: HIV Med. 2019 Mar 29;20(5):317–329. doi: 10.1111/hiv.12726

Table 3a:

Mortality risk by diagnosis of major depressive disorder (defined by ICD-9 code) in the Veterans Aging Cohort Study (VACS)

	Model 1		Model 2		Model 3^*
	Hazard ratio [95% CI]	p-value	Hazard ratio [95% CI]	p-value	Hazard ratio [95% CI]	p-value
No major depressive disorder	1 (ref)	<0.01	1 (ref)	<0.01	1 (ref)	0.02
Major depressive disorder	1.09 [1.06, 1.13]	<0.01	1.23 [1.20, 1.27]	<0.01	1.04 [1.01, 1.07]	0.02

Model 3B includes an interaction term for major depressive disorder diagnosis and HIV status. The p-value for this interaction term was 0.02

Model 1 is adjusted for HIV status only. Model 2 additionally adjusted Model 1 for age, sex, and race. Model 3 additionally adjusted Model 2 for baseline cardiovascular disease, chronic obstructive pulmonary disease, cancer, diabetes, systolic blood pressure, diastolic blood pressure, total cholesterol, estimated glomerular filtration rate, hemoglobin, and hepatitis C seropositivity.