Table 3.
Relationship between Body Mass Index (BMI) at Age 18 and Risk of SLE among 55,951 women in the Black Women’s Health Study
| BMI at age 18 (kg/m2) |
Cases/person- years |
Age and questionnaire period- adjusted HR (95%CI)* |
Multivariable-adjusted HR (95%CI)** |
|---|---|---|---|
| < 20 | 49/378,566 | 1.10 (0.74, 1.63) | 1.05 (0.71, 1.56) |
| 20–24.9 | 51/412,108 | Ref. | Ref. |
| 25–29.9 | 15/90,642 | 1.28 (0.72, 2.28) | 1.25 (0.70, 2.23) |
| 30+ | 12/37,132 | 2.48 (1.32, 4.67) | 2.38 (1.26, 4.51) |
HR=hazard ratio; CI=confidence interval
Model 1: adjusted for age and period
Model 2: adjusted for age, period, age began alcohol intake (≤ 20 years), age began smoking (≤ 18 years), age began use of oral contraceptives (≤ 18 years of age), vigorous activity at age 21, age at menarche, and parental education.