Table 3. Comparisons of dosimetric values, as well as of respiratory and exercise test results, between patients who underwent supraclavicular lymph node irradiation and those who did not.
Variable | SCLN irradiation | p | |
---|---|---|---|
No | Yes | ||
Dosimetric value | |||
Mean lung dose, cGy | 539.2 ± 168.1 | 738.5 ± 339.5 | 0.10 |
V25 ,cm3 | 114.6 ± 53 | 203.9 ± 127.8 | 0.10 |
V25% | 6.9 ± 3.0 | 11.7 ± 6.4 | 0.04 |
Respiratory and exercise test | |||
Muscle strength, cmH2O Σ MIP Σ MEP |
25.0 ± 16.3 15.5 ± 15.1 |
24.7 ± 14.6 22.6 ± 16.5 |
0.98 0.27 |
Chest wall mobility, cm Σ Axillary Σ Xiphoid |
1.3 ± 1.0 1.0 ± 1.4 |
1.7 ± 0.8 1.9 ± 1.2 |
0.21 0.03 |
Pulmonary function test Σ FVC, L Σ FEV1, L |
0.14 ± 0.22 0.11 ± 0.2 |
0.23 ± 0.23 0.16 ± 0.17 |
0.13 0.19 |
Exercise test Σ Workload, Watts VO2peak, mL/kg/min |
4.2 ± 1.49 0.96 ± 3.0 |
17.4 ± 22.0 0.98 ± 2.1 |
0.21 0.98 |
SCLN: supraclavicular lymph node; V25: ipsilateral lung volume receiving 25 Gy; and VO2peak: oxygen uptake at peak exercise.