Table 4. Variation in respiratory muscle strength, chest wall mobility, pulmonary function testing, and cardiopulmonary exercise testing before and after three months of radiotherapy.

Variable	Pre-RT	Post-RT	p
Muscle strength, cmH2O Σ MIP Σ MEP	−95.6 ± 22.4 100.0 ± 23.0	−71.8 ± 14.7 80.9 ± 16.8	0.0001 0.0001
Chest wall mobility, cm Σ Axillary Σ Xiphoid	4.1 ± 0.9 3.0 ± 1.7	2.5 ± 0.7 1.6 ± 1.4	0.0001 0.0001
MVV, L/min	124.0± 33.6	111 ± 32.6	0.0001
Pulmonary function test Σ FVC, L Σ FEV1, L Σ IC, L Σ TLC, L Σ DLCO, mL/min/mmHg	3.0 ± 0.8 2.4 ± 0.6 2.3 ± 0.5 4.7 ± 1.0 21.4 ± 4.5	2.8 ± 0.7 2.2 ± 0.6 2.1 ± 0.6 4.5 ± 0.9 21.13 ± 4.5	0.0001 0.0001 0.008 0.01 0.56
Cardiopulmonary exercise test
Workload, Watts Σ VO2peak, mL/kg/min Σ VEpeak, L/min Σ RERpeak Σ RRpeak, breaths/min Σ VTpeak , L	96.5 ± 30 16.8 ± 3.0 51.4 ± 14.0 1.2 ± 0.1 35.6 ± 6.6 1.4 ± 0.3	88.0 ± 20.8 15.6 ± 3.9 45.0 ± 11.9 1.1 ± 0.1 34.7 ± 5.9 1.2 ± 0.2	0.04 0.04 0.01 0.009 0.46 0.003
Dynamic relationship Σ Metabolic (∆VO2/∆W) Σ Respiratory (∆VE/∆VCO2) Σ Cardiovascular (∆HR/∆VO2)	9.2 ± 1.6 33.1 ± 5.0 73.6 ± 18.6	10.0 ± 1.5 31.4 ± 5.5 75.2 ± 18.2	0.02 0.07 0.50

RT: radiotherapy; MVV: maximal voluntary ventilation; IC: inspiratory capacity; VO_2peak: oxygen uptake at peak exercise; V_Epeak: minute ventilation at peak exercise; RER_peak: respiratory exchange ratio at peak exercise; and ∆VCO₂: carbon dioxide output.