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. 2019 Apr 11;9:5928. doi: 10.1038/s41598-019-42411-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Microscopic pattern found in the pancreas of the TP-G group (A–C). In this group the loss of the acinar component showed a lobular pattern, with lobules without atrophy (score 0) (*), lobules with irregular and moderate atrophy (score 3) (#), and others with complete disappearance of exocrine pancreatic tissue (score 5) (◆). The glue can be seen inside the ducts of the atrophied lobes (black arrow). In these ducts surrounded by multinucleated cells there is also an obvious foreign body reaction (red arrow).