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. 2019 Apr 11;9:5937. doi: 10.1038/s41598-019-42315-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of ITA on growth of Vibrio sp. and isocitrate and isocitrate lyase (ICL). (a) The absorbance (600 nm) of Vibrio sp. cultured in different ITA concentrations (0, 3 and 6 mM) supplemented with sodium acetate over 24 h. (b) Level of isocitrate in the 3 mM ITA treatment and the control at 24 hpi. (c) Activity of ICL in the 3 mM ITA treatment and the control at 24 hpi. Data are presented as mean ± S.D. (n = 6). Significant differences relative to the control are marked with an asterisk (*) (t-test, p < 0.05).