Table 4.
Relevance information about herbs and compounds (determined to have effects in treating pain) with regard to pain.
| Herb/compound | n | k | Number of directly targeted pain disease proteins | Percentage (k/n) | Sum score | Max score | P-Value | Type |
|---|---|---|---|---|---|---|---|---|
| Salvia miltiorrhizae (herb) | 99 | 58 | 4 | 0.586 | 14.97 | 0.54 | 0.00 | known |
| Ursolic acid | 16 | 13 | 1 | 0.812 | 3.65 | 0.54 | 0.00 | known |
| Baicalin | 23 | 13 | 0 | 0.565 | 2.17 | 0.42 | 9.55E-15 | known |
| Rosmarinic acid | 7 | 6 | 1 | 0.857 | 1.33 | 0.37 | 4.23E-09 | known |
| Ferulic acid | 16 | 7 | 0 | 0.438 | 1.08 | 0.36 | 1.64E-07 | known |
| Tanshinone I | 7 | 5 | 0 | 0.714 | 1.07 | 0.45 | 4.25E-07 | unknown |
| Caffeic acid | 20 | 5 | 1 | 0.250 | 1.04 | 0.40 | 2.28E-04 | known |
| Tanshinone IIA | 11 | 8 | 1 | 0.727 | 0.93 | 0.22 | 8.05E-11 | known |
| Protocatechuic acid | 4 | 3 | 1 | 0.750 | 0.76 | 0.43 | 9.75E-05 | known |
| Tetramethylpyrazine | 3 | 2 | 0 | 0.667 | 0.73 | 0.49 | 2.51E-3 | known |
| Cryptotanshinone | 4 | 3 | 1 | 0.750 | 0.63 | 0.35 | 9.75E-05 | unknown |
| Gamma-Sitosterol | 4 | 4 | 0 | 1.000 | 0.52 | 0.15 | 7.28E-07 | known |
| Magnesium lithospermate B | 5 | 3 | 1 | 0.600 | 0.44 | 0.19 | 2.39E-04 | unknown |
| Isoferulic acid | 3 | 2 | 0 | 0.667 | 0.16 | 0.12 | 2.51E-03 | unknown |
| Danshensu | 2 | 2 | 0 | 1.000 | 0.12 | 0.06 | 8.54E-04 | unknown |
| Panax notoginseng (herb) | 143 | 43 | 7 | 0.301 | 17.78 | 0.67 | 0.00 | known |
| Eicosanetetraenoic acid | 39 | 16 | 5 | 0.410 | 4.90 | 0.67 | 5.00E-15 | unknown |
| Hexadecanoic acid | 48 | 15 | 2 | 0.313 | 3.21 | 0.63 | 4.15E-12 | unknown |
| Polysaccharide | 14 | 14 | 0 | 1.000 | 3.13 | 0.53 | 0.00 | known |
| Ginsenoside Rd | 3 | 3 | 1 | 1.000 | 1.96 | 0.62 | 2.49E-05 | unknown |
| Ginsenoside Rg2 | 3 | 3 | 0 | 1.000 | 1.60 | 0.36 | 2.49E-05 | unknown |
| Ginsenoside Re | 4 | 4 | 0 | 1.000 | 0.79 | 0.39 | 7.28E-07 | unknown |
| Pentadecanoic acid | 2 | 2 | 0 | 1.000 | 0.71 | 0.33 | 8.54E-04 | unknown |
| Gamma-Sitosterol | 4 | 4 | 0 | 1.000 | 0.52 | 0.15 | 7.28E-07 | known |
| Ginsenoside Rg3 | 4 | 3 | 0 | 0.750 | 0.28 | 0.13 | 9.75E-05 | known |
| Ginsenoside Rg1 | 5 | 2 | 1 | 0.400 | 0.22 | 0.14 | 8.05E-03 | known |
| Dauricine | 1 | 1 | 0 | 1.000 | 0.17 | 0.17 | 2.92E-02 | unknown |
| Borneolum (herb) | 17 | 11 | 0 | 0.647 | 1.80 | 0.37 | 1.38E-13 | known |
| Oleanolic acid | 14 | 9 | 0 | 0.643 | 1.78 | 0.37 | 2.70E-11 | known |
| Asiatic acid | 3 | 2 | 0 | 0.667 | 0.03 | 0.03 | 2.51E-03 | unknown |
Lines 2, 17 and 29 are herbal items. Compounds below an herb belong to this herb. The “Materials and methods” section contains definitions for n and k.