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. 2019 Apr 11;9:5907. doi: 10.1038/s41598-019-42322-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Distribution of network hub nodes based on C_D,node, C_B,node and C_P,node. (A) Network hub nodes based on C_D,node are highlighted by the red circles. (B) Network hub nodes based on C_B,node are highlighted by the red circles. (C) Network hub nodes based on C_P,node are highlighted by the red circles. The network hub nodes were identified when the network nodes were greater than one standard deviation (SD) above the mean of each nodal centrality measure map. The size of each circle indicates the strength of each centrality measure.