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. 2019 Apr 11;9:5920. doi: 10.1038/s41598-019-42551-w

Table 1.

Plasma levels of TLR9 activity, neutrophil activation markers and pro-inflammatory cytokine IL-8 in patients with preterm and term preeclampsia.

Neutrophil markers 15 weeks (Preterm N = 19) 15 weeks (Term N = 38) P Value 20 weeks (Preterm N = 19) 20 weeks (Term N = 37) P Value TOD (Preterm N = 6) TOD (Term N = 16) P Value
TLR9 Signal 0.31 ± 0.05 0.27 ± 0.03 0.66 0.30 ± 0.06 0.29 ± 0.03 0.41 0.37 ± 0.03 0.39 ± 0.04 0.713
Calprotectin (ng/ml) 1043.15 ng/ml ± 126.19 1645.66 ng/ml ± 187.30 0.16 886.99 ± ng/ml 245.48 1167.96 ng/ml ± 77.80 0.57 1878.35 ng/ml ± 424.90 2055.57 ng/ml ± 170.62 0.77
MPO (ng/ml) 4.42 ng/ml [1.77–10.25] 6.58 ng/ml [2.11–9.70] 0.56 4.55 ng/ml [2.48–8.74] 6.15 ng/ml [2.96–21.46] 0.84 8.59 ng/ml [4.72–11.87] 8.33 ng/ml [5.67–14.78] 0.43
MMP8 (pg/ml) 1138.41 pg/ml ± 149.24 989.38 pg/ml ± 113.31 0.25 1097.48 pg/ml ± 108.58 1098.46 pg/ml ± 88.69 0.97 1775.73 pg/ml ± 466.30 1263.75 pg/ml ± 182.92 0.12
IL-8 (pg/ml) 32.09 pg/ml [7.40–192.91] 8.12 pg/ml [2.19–18.25] 0.17 22.92 pg/ml [4.76–188.69] 12.67 pg/ml [2.11–18.23] 0.32 24.63 pg/ml [2.68–47.59] 24.63 pg/ml [9.78–75.14] 0.81

Data is presented as mean ± SEM and median (25–75 percentiles) where applicable.