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. 2019 Apr 11;9:5953. doi: 10.1038/s41598-019-42227-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Evaluation of phylogenetic versus spatial effect. HGT ratio represents the total number of one-to-one (A), one-to-many (B), and many-to-many (C) HGT events detected on a gene tree divided by the total number of HGT events (i.e. the sum of one-to-one, one-to-many, and many-to-many) detected on that gene tree. Phylogenetically similar microorganisms (PS) belong to the same genus. Phylogenetically diverse microorganisms (PD) belong to different genera. Similar habitat (SH) implies microorganisms harboring the same body site or niche. Different habitats (DH) imply microorganisms residing in different body sites or niches. See Supplementary Table S6 for P-values, pairwise Mann–Whitney U test.