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. 2019 Apr 5;10:315. doi: 10.3389/fgene.2019.00315

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Copyright © 2019 Lin, Beckers, Mc Cafferty, Gansemans, Joanna Szymańska, Chaitanya Pavani, Catani, Van Nieuwerburgh, Deforce, De Sutter, Van Soom and Peelman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miRNAs’ differential expression between embryos with different cleavage patterns and different blastocyst formation. (A,B) The relative expression levels of miR-30c and miR-10b between the CM of fast, intermediate and slow developing embryos were detected using RT-qPCR. (C,D) Relative expression of miRNAs between CM of degenerate embryos and blastocyst. (E) Relative expression of miR-30c between conditioned media and control media. (F) Relative expression of miR-30c and miR-10b between the intermediate and slow developing embryos. (G,H) Relative expression of miRNAs between CM of degenerate embryos and blastocyst. Data are presented as mean ± SD of three experiments. (^∗P < 0.05, ^∗∗P < 0.01, n.s, no significance).