Figure 4.

Mutants defective in inheritance of small RNAs and histone methylations are also longer, if they derive from ancestors that were grown in liquid. The normalized lengths of progeny of liquid-grown worms mutated in genes involved in small RNA biogenesis and inheritance (hrde-1, nrde-3, rrf-1, rrf-3, rde-1, rde-4 and mut-16 mutants) or chromatin methylation (set-25, set-32 and met-2; set-25 mutants) are presented. N > 100 per group. ****p < 0.0001, ***p = 0.0001, **p = 0.0084, one-way ANOVA, Sidak's multiple comparisons test. Error bars represent standard deviations.